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KMID : 0357919990330111102
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Korean Journal of Pathology
1999 Volume.33 No. 11 p.1102 ~ p.1106
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Polyvesicular Vitelline Tumor of the Ovary - A case report -
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Moon Woo-Sung
Lee Dong-Geun
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Abstract
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Polyvesicular vitelline tumor of the ovary is an extremely rare variant of yolk sac tumor. We present a case of pure polyvesicular vitelline tumor in a 43-year-old woman. Light microscopy revealed a predominantly polyvesicular pattern embedded in mesoblastic stroma with the cysts showing two type of lining; tall columnar and cuboidal, or mesothelioid cells. The lining atypical cells showed occasional mitoses and intracytoplasmic PAS positive hyaline globules. In some areas, the cystic space contained a large amount of intraluminal hyaline material. Immunohistochemically, alpha- fetoprotein and alpha-1-antitrypsin were detected as a fine granular deposit in the cytoplasm of epithelial cells and hyaline globules. Electron microscopically, marked specialization of the vesicular lining cells suggested a differentiation toward gut structures and mature yolk sac.
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KEYWORD
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Ployvesicular vitelline tumor, Yolk sac
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